Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.53 |
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467287 | 0.82 | FOLH1 (0.52) | — | |
| SCHEMBL7929474 | 0.82 | GRIK1 (0.46) | — | |
| SCHEMBL1861903 | 0.80 | GRIK1 (0.59) | — | |
| SCHEMBL3468867 | 0.78 | GRIA2 (0.51) | NPC1RAB9A | |
| SCHEMBL3467381 | 0.77 | SLC7A5 (0.50) | — | |
| SCHEMBL7918296 | 0.77 | MMP2 (0.56) | — | |
| SCHEMBL11641113 | 0.75 | FOLH1 (0.59) | — | |
| SCHEMBL3466490 | 0.74 | CYP17A1 (0.52) | — | |
| SCHEMBL7932591 | 0.74 | MMP12 (0.63) | — | |
| SCHEMBL3467260 | 0.74 | MMP2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |