Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.33 |
| ▸ | PDE4A | P27815 | 8/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2500685 | 0.89 | ADORA2A (0.35) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9893563 | 0.83 | CYP1A2 (0.30) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26093015 | 0.82 | MAPK1 (0.33) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2499767 | 0.79 | RGS4 (0.37) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26092754 | 0.76 | ADORA2A (0.34) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15369262 | 0.75 | CYP3A4 (0.42) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15369263 | 0.75 | CYP3A4 (0.42) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3403624 | 0.74 | PDE4A (0.30) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26093327 | 0.73 | ADORA2B (0.35) | ADORA2AADORA2BCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL426716 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068016-A1 | PAINT COMPOSITION, COATED ARTICLE, AND METHOD FOR FORMING CURED FILM | 信越化学工業株式会社 | 2023-04-27 | — | — | WO | disclosed |
| EP-0735086-B1 | 1-Component alkoxy curing RTV silicone sealant compositions | GEN ELECTRIC (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-0735086-A2 | 1-Component alkoxy curing RTV silicone sealant compositions | GENERAL ELECTRIC COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5519104-A | DIALKYLTIN DIALKANOATE CURING CATALYST | GENERAL ELECTRIC COMPANY (US) | 1996-05-21 | — | — | US | disclosed |