Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911467 | 0.79 | ALDH1A1 (0.39) | L3MBTL1HPGDMAPTPOLBAVPR1A | |
| SCHEMBL16167675 | 0.79 | ALDH1A1 (0.39) | L3MBTL1TSHRHPGDMAPTANO1 | |
| SCHEMBL7908197 | 0.78 | ALDH1A1 (0.38) | HPGDMAPTAVPR1APTK2LRRK2 | |
| SCHEMBL7914828 | 0.77 | AVPR1A (0.39) | TSHRHPGDMAPTAVPR1APTK2 | |
| SCHEMBL7909318 | 0.76 | AVPR1A (0.37) | L3MBTL1HPGDMAPTAVPR1ALRRK2 | |
| SCHEMBL7908194 | 0.76 | KMT2A (0.38) | TSHRHPGDMAPTAVPR1APTK2 | |
| SCHEMBL16167674 | 0.75 | AVPR1A (0.37) | HPGDMAPTPOLBAVPR1APTK2 | |
| SCHEMBL2504845 | 0.74 | AVPR2 (0.48) | AVPR1A | |
| SCHEMBL7909327 | 0.74 | AVPR1A (0.39) | L3MBTL1HPGDMAPTPOLBAVPR1A | |
| SCHEMBL16167673 | 0.74 | HSD11B1 (0.40) | L3MBTL1AVPR1AKMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859601-B2 | Substituted benzyl and phenylsulfonyl triazolones, and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| US-8859601-B2 | Substituted benzyl and phenylsulfonyl triazolones, and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| WO-2010063402-A1 | SUBSTITUTED BENZYL AND PHENYLSULFONYL TRIAZOLONES, AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-10 | — | — | WO | disclosed |