Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | CCR8 | P51685 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915988 | 0.88 | HTR5A (0.39) | PGK1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL16502765 | 0.86 | TP53 (0.43) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7913836 | 0.84 | KDM4E (0.36) | PGK1KDM4ETTK | |
| SCHEMBL7908662 | 0.82 | PLA2G2D (0.40) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7914783 | 0.81 | GABRG2 (0.34) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16502836 | 0.77 | HTR5A (0.53) | HTR5A | |
| SCHEMBL7913827 | 0.76 | ALOX15 (0.36) | KDM4ENPC1MAPTRAB9ATP53 | |
| SCHEMBL16502675 | 0.76 | TP53 (0.43) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7911006 | 0.75 | HDAC8 (0.40) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16503491 | 0.75 | HTR2A (0.39) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |