Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 5/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | FASN | P49327 | 2/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509549 | 0.82 | TP53 (0.41) | L3MBTL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL16503571 | 0.79 | MCL1 (0.35) | L3MBTL1GAASLC22A12KDM4EFASN | |
| SCHEMBL7916729 | 0.77 | SLC22A12 (0.42) | SLC22A12KDM4EGRIA1CACNG8MEN1 | |
| SCHEMBL7923274 | 0.72 | HTR2B (0.47) | CYP2D6 | |
| SCHEMBL16502488 | 0.69 | TP53 (0.47) | L3MBTL1GAAKDM4EMEN1NPC1 | |
| SCHEMBL16502476 | 0.69 | ABL1 (0.43) | L3MBTL1SLC22A12KDM4EMEN1NPC1 | |
| SCHEMBL16502474 | 0.69 | NPC1 (0.41) | L3MBTL1GAASLC22A12F10KDM4E | |
| SCHEMBL16502478 | 0.68 | ALDH1A1 (0.41) | GAASLC22A12KDM4EMEN1NPC1 | |
| SCHEMBL10064207 | 0.68 | L3MBTL1 (0.45) | L3MBTL1GAASLC22A12KDM4EMEN1 | |
| SCHEMBL16502466 | 0.66 | KIF11 (0.43) | L3MBTL1GAAF10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |