Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916729 | 0.85 | SLC22A12 (0.42) | SLC22A12GRIA1CACNG8PPARGRORC | |
| SCHEMBL16509549 | 0.81 | TP53 (0.41) | L3MBTL1HTTMEN1ALDH1A1MAPT | |
| SCHEMBL7918374 | 0.79 | L3MBTL1 (0.34) | SLC22A12GRIA1CACNG8L3MBTL1FASN | |
| SCHEMBL7923274 | 0.77 | HTR2B (0.47) | CYP2C9CYP2C19 | |
| SCHEMBL16503550 | 0.72 | KDM4E (0.36) | RORCKDM4EMEN1KMT2A | |
| SCHEMBL16503577 | 0.71 | ESR1 (0.34) | HTTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7908665 | 0.71 | PLA2G2D (0.49) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL7920119 | 0.71 | PLA2G2D (0.44) | SLC22A12PPARGRORC | |
| SCHEMBL16502478 | 0.71 | ALDH1A1 (0.41) | SLC22A12CA1CA2GAAXDH | |
| SCHEMBL16503582 | 0.70 | LMNA (0.34) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394987-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2011-12-14 | — | — | EP | disclosed |