Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914895 | 0.86 | THRB (0.57) | THRBMAPTGAAKDRMAPK1 | |
| SCHEMBL7918619 | 0.86 | THRB (0.69) | THRBMAPTGAAKDRMAPK1 | |
| SCHEMBL7913341 | 0.84 | NPSR1 (0.67) | THRBMAPTGAAKDRTP53 | |
| SCHEMBL7904829 | 0.84 | THRB (0.66) | THRBMAPTGAAKDRMAPK1 | |
| SCHEMBL7912098 | 0.82 | THRB (0.64) | THRBMAPTGAAKDRMAPK1 | |
| SCHEMBL7918511 | 0.82 | MAPT (0.65) | THRBMAPTGAAKDRMAPK1 | |
| SCHEMBL7914872 | 0.82 | THRB (0.64) | THRBMAPTGAAKDRMAPK1 | |
| SCHEMBL7914864 | 0.80 | NPSR1 (0.61) | THRBMAPTGAAKDRNPSR1 | |
| SCHEMBL7913339 | 0.80 | THRB (0.62) | THRBMAPTGAAKDRMAPK1 | |
| SCHEMBL12696197 | 0.78 | HSD11B1 (0.57) | MAPTTP53NPSR1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |