Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856411 | 0.83 | HPGD (0.63) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10421957 | 0.79 | RAB9A (1.00) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL7919296 | 0.77 | RAB9A (0.76) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL9113979 | 0.76 | RAB9A (0.69) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL10508468 | 0.74 | RAB9A (0.76) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL8618065 | 0.74 | NPC1 (0.76) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL16444039 | 0.73 | RAB9A (0.69) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL10458108 | 0.70 | CYP1A2 (1.00) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL9856352 | 0.70 | MAOA (0.42) | LMNATSHRHPGD | |
| SCHEMBL9856284 | 0.70 | CA2 (0.43) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |