Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.63 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165456 | 0.88 | GABRA1 (0.63) | GABRA1GABRB2ESR1RNASEH1HPGD | |
| SCHEMBL29664138 | 0.83 | GABRA1 (0.58) | GABRA1GABRB2RNASEH1HPGDHSD17B10 | |
| SCHEMBL920814 | 0.82 | ESR1 (0.50) | GABRA1GABRB2ESR1PDCD1ESR2 | |
| SCHEMBL5877825 | 0.79 | GABRA1 (0.68) | GABRA1GABRB2ESR1HPGDHSD17B10 | |
| SCHEMBL3287169 | 0.78 | ALOX5 (0.47) | GABRA1GABRB2ESR1PDCD1ESR2 | |
| SCHEMBL318750 | 0.78 | GABRA1 (1.00) | GABRA1GABRB2ESR1HPGDHSD17B10 | |
| SCHEMBL3960601 | 0.78 | GABRA1 (0.66) | GABRA1GABRB2HPGDHSD17B10KDM4E | |
| SCHEMBL17069247 | 0.76 | GABRA1 (0.63) | GABRA1GABRB2HPGDHSD17B10USP2 | |
| SCHEMBL11498104 | 0.76 | GABRA1 (0.36) | GABRA1GABRB2ESR1PDCD1ESR2 | |
| SCHEMBL2096847 | 0.76 | GABRA1 (0.63) | GABRA1GABRB2HPGDKDM4EALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6217995-B1 | TRANSPARENT POLYCARBONATE OR POLYESTERCARABONATE CONTAINING CYCLIC ALIPHATIC GROUP, HAVING A VISIBLE LIGHT TRANSMITTANCE MORE THAN 80% AND A GLASS TRANSITION TEMPERATURE LESS THAN 80 DEGREE C. EXHIBIT BIREFRINGENCE INDEX LESS THAN 15 NM | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-04-17 | — | — | US | disclosed |