Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.66 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.66 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15667381 | 0.86 | AMY1A (0.53) | GABRA1GABRB2AMY1ATRPA1TP53 | |
| SCHEMBL15666912 | 0.86 | AMY1A (0.53) | GABRA1GABRB2AMY1ATRPA1TP53 | |
| SCHEMBL15666913 | 0.86 | AMY1A (0.53) | GABRA1GABRB2AMY1ATRPA1TP53 | |
| SCHEMBL14478234 | 0.84 | AMY1A (0.52) | GABRA1GABRB2AMY1ATRPA1TP53 | |
| SCHEMBL3953639 | 0.83 | TRPA1 (0.50) | GABRA1GABRB2AMY1ATRPA1TP53 | |
| SCHEMBL23153076 | 0.82 | AMY1A (0.50) | GABRA1GABRB2AMY1ATRPA1TP53 | |
| SCHEMBL806464 | 0.82 | AMY1A (0.50) | GABRA1GABRB2AMY1ATRPA1TP53 | |
| SCHEMBL5877825 | 0.81 | GABRA1 (0.68) | GABRA1GABRB2TRPA1TP53TDP1 | |
| SCHEMBL1581538 | 0.80 | GABRA1 (0.61) | GABRA1GABRB2TRPA1TP53TDP1 | |
| SCHEMBL6278017 | 0.79 | AMY1A (0.70) | GABRA1GABRB2AMY1ATRPA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115243764-B | Heterocyclic derivatives as TRMP antagonists | 奇华顿股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20230098332-A1 | HETEROCYCLIC DERIVATIVES AS TRMP8 ANTAGONISTS | GIVAUDAN SA (CH) | 2023-03-30 | — | — | US | disclosed |
| EP-4114523-A1 | HETEROCYCLIC DERIVATIVES AS TRMP8 ANTAGONISTS | Givaudan SA (CH) | 2023-01-11 | — | — | EP | disclosed |
| CN-115243764-A | Heterocyclic derivatives as TRMP8 antagonists | 奇华顿股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| US-10960088-B2 | Macrocycles, cobalt and iron complexes of same, and methods of making and using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-03-30 | — | — | US | disclosed |
| US-10422047-B2 | Electrochemical process for coupling of phenol to aniline | EVONIK DEGUSSA GMBH (DE) | 2019-09-24 | — | — | US | disclosed |
| US-20180030244-A1 | Alternative Methods to Control Crosslinking in High Impact Polystyrene | FINA TECHNOLOGY (US) | 2018-02-01 | — | — | US | disclosed |
| US-9809699-B2 | Alternative methods to control crosslinking in high impact polystyrene | FINA TECHNOLOGY, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170121501-A1 | ALTERNATIVE METHODS TO CONTROL CROSSLINKING IN HIGH IMPACT POLYSTYRENE | FINA TECHNOLOGY, INC. | 2017-05-04 | — | — | US | disclosed |
| EP-2964810-B1 | ELECTROCHEMICAL METHOD FOR COUPLING PHENOL TO ANILINE | EVONIK DEGUSSA GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| WO-2002100910-A1 | MOLYBDENUM-BASED CATALYST COMPOSITION FOR PRODUCING SYNDIOTACTIC 1,2-POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2002-12-19 | — | — | WO | disclosed |
| WO-2002075420-A1 | COLORED RADIATION CURABLE COATING COMPOSITIONS FOR IDENTIFYING TELECOMMUNICATIONS ELEMENTS AND TELECOMMUNICATIONS ELEMENTS COATED THEREBY | ALCATEL (FR) | 2002-09-26 | — | — | WO | disclosed |
| WO-1998058911-A2 | PROSTAGLANDIN AGONISTS | PFIZER INC. (US) | 1998-12-30 | — | — | WO | disclosed |
| EP-0485472-A1 | BIS-CYCLIC PHOSPHITE COMPOUNDS AND POLYMERIC MATERIALS STABILIZED THEREWITH | EASTMAN KODAK COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| EP-0437493-A1 | CYCLIC PHOSPHITES AND STABILIZED POLYMERIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1991-07-24 | — | — | EP | disclosed |
| WO-1991001987-A1 | BIS-CYCLIC PHOSPHITE COMPOUNDS AND POLYMERIC MATERIALS STABILIZED THEREWITH | EASTMAN KODAK COMPANY (US) | 1991-02-21 | — | — | WO | disclosed |
| US-4956406-A | Oxidation resistance of polypropylene or copolymers also heat resistance and radiation resistance | EASTMAN KODAK COMPANY (US) | 1990-09-11 | — | — | US | disclosed |
| US-4929654-A | HEAT RESISTANCE, LIGHT RESISTANCE | EASTMAN KODAK COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| WO-1990003976-A1 | CYCLIC PHOSPHITES AND STABILIZED POLYMERIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1990-04-19 | — | — | WO | disclosed |
| EP-0363270-A1 | Cyclic phosphites and stabilized polymeric compositions | EASTMAN KODAK COMPANY (US) | 1990-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230098332-A1 | HETEROCYCLIC DERIVATIVES AS TRMP8 ANTAGONISTS | TRPM8, TRPM7, TRPM5 | GABRA1 1927/4885GABRB2 1044/4885AMY1A 3990/4885 |
| US-10960088-B2 | Macrocycles, cobalt and iron complexes of same, and methods of making and using same | ABCB7, FECH, CYC1 | GABRA1 3802/4885GABRB2 3775/4885AMY1A 3991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.