Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919361 | 0.83 | GABRA1 (0.63) | GABRA1GABRB2ALDH1A1USP2GAA | |
| SCHEMBL5165456 | 0.83 | GABRA1 (0.63) | GABRA1GABRB2ALDH1A1USP2GAA | |
| SCHEMBL2284641 | 0.83 | ESR1 (0.48) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL29508269 | 0.81 | ADRB2 (0.51) | PKMBCHETYRACHECYP17A1 | |
| SCHEMBL5710230 | 0.81 | GABRA1 (0.49) | GABRA1GABRB2ALOX15TYRTSHR | |
| SCHEMBL28292411 | 0.80 | BCHE (0.43) | GABRA1GABRB2ALDH1A1USP2GAA | |
| SCHEMBL1986274 | 0.80 | ALOX5 (0.46) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL6246037 | 0.77 | TYR (0.47) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL3292528 | 0.77 | ESR1 (0.46) | ALDH1A1USP2GAAPKMHPGD | |
| SCHEMBL3934205 | 0.77 | TDP1 (0.56) | ALDH1A1HPGDALOX15HSD17B10BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4004080-A1 | POLY(ARYLENE ETHER) COMPOSITIONS | SHPP Global Technologies B.V. (NL) | 2022-06-01 | — | — | EP | disclosed |