Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927420 | 0.96 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL7927317 | 0.72 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL7919502 | 0.71 | L3MBTL1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7930363 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL7930864 | 0.71 | POLB (0.33) | ALDH1A1SMN1; SMN2CHRM2CHRM4CHRM1 | |
| SCHEMBL7925722 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL7927563 | 0.70 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8169909 | 0.69 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2CHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL7927319 | 0.69 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2CHRM2CHRM4CHRM1 | |
| SCHEMBL7928351 | 0.69 | POLB (0.32) | ALDH1A1SMN1; SMN2CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0867454-B1 | POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS | IDEMITSU KOSAN CO (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6075102-A | Polymerization catalyst and process for producing polymers | IDEMITSU KOSAN CO., LTD. (JP) | 2000-06-13 | — | — | US | disclosed |
| EP-0867454-A1 | POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-09-30 | — | — | EP | disclosed |