Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919799 | 0.87 | PTGES (0.60) | PDE7AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL10503654 | 0.84 | FNTA (0.58) | ALDH1A1CYP3A4ALOX15TDP1MEN1 | |
| SCHEMBL2963062 | 0.83 | LMNA (0.64) | PDE7AALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10507254 | 0.83 | PDE7A (0.61) | PDE7AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL11074249 | 0.82 | PDE7A (0.50) | PDE7AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL26676263 | 0.82 | HSP90AA1 (0.53) | PDE7AALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5240597 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4ALOX15TDP1MEN1 | |
| SCHEMBL23879982 | 0.81 | MAPT (0.58) | PDE7AALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL19969740 | 0.81 | ALDH1A1 (0.60) | ALDH1A1CYP3A4ALOX15TDP1MEN1 | |
| SCHEMBL2728411 | 0.80 | ALDH1A1 (0.58) | ALDH1A1CYP3A4ALOX15TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291442-B1 | Pharmacological modulators of voltage-gated potassium ion channels | THE GENERAL HOSPITAL CORPORATION | 2001-09-18 | — | — | US | disclosed |
| EP-0207350-B1 | PROCESS FOR PREPARING DIARYL SULPHIDES | CASSELLA Aktiengesellschaft (DE) | 1989-01-18 | — | — | EP | disclosed |
| US-4686303-A | Process for the preparation of diaryl sulphides | CASSELLA AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0207350-A1 | Process for preparing diaryl sulphides | CASSELLA Aktiengesellschaft (DE) | 1987-01-07 | — | — | EP | disclosed |