Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.40 |
| ▸ | HRH1 | P35367 | 6/20 | 0.40 |
| ▸ | HRH2 | P25021 | 5/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920300 | 0.81 | CYP3A4 (0.41) | CYP3A4CYP2D6HRH3HRH1HRH2 | |
| SCHEMBL10620158 | 0.80 | LSS (0.54) | CYP3A4CYP2D6HRH3HRH1KDM4E | |
| SCHEMBL7916849 | 0.79 | CYP2D6 (0.43) | CYP3A4CYP2D6HRH3HRH1HRH2 | |
| SCHEMBL7914886 | 0.77 | CALM1 (0.33) | — | |
| SCHEMBL184515 | 0.74 | MMP2 (0.34) | HRH3HRH1HRH2MMP2MMP3 | |
| SCHEMBL4783831 | 0.73 | HDAC3 (0.54) | HRH3KDM4ELMNAMAPTHDAC1 | |
| SCHEMBL5574693 | 0.73 | HDAC3 (0.54) | HRH3KDM4ELMNAMAPTHDAC1 | |
| SCHEMBL4864438 | 0.73 | HRH3 (0.53) | HRH3HRH1HRH2MMP2MMP3 | |
| SCHEMBL7917085 | 0.73 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL7914185 | 0.72 | MMP2 (0.41) | CYP3A4CYP2D6MMP2MMP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6217943-B1 | ADHESION AND REINFORCEMENT WITH SILANE CYANATE COUPLERS | 3M INNOVATIVE PROPERTIES COMPANY | 2001-04-17 | — | — | US | disclosed |
| US-5912377-A | CONTAINING AT LEAST ONE CYANATE ESTER GROUP AND HYDROLYZABLE SILYL GROUP; REINFORCED COMPOSITES, ADESIVES, COATINGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0830410-B1 | AROMATIC CYANATE ESTER SILANE COUPLING AGENTS | MINNESOTA MINING & MFG (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0830410-A1 | AROMATIC CYANATE ESTER SILANE COUPLING AGENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996039457-A1 | AROMATIC CYANATE ESTER SILANE COUPLING AGENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-12 | — | — | WO | disclosed |