Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391086 | 0.84 | KDM4E (0.54) | ALDH1A1LMNAKDM4EGLAGAA | |
| SCHEMBL1390747 | 0.82 | ALOX5 (0.37) | ALOX5ALDH1A1USP2HTTTAS1R3 | |
| SCHEMBL1390756 | 0.82 | HTT (0.54) | ALDH1A1USP2HTTMMP2ADAM17 | |
| SCHEMBL31301099 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TAS1R3TAS1R1LMNAKDM4E | |
| SCHEMBL4499439 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TAS1R3TAS1R1LMNAKDM4E | |
| SCHEMBL7924591 | 0.80 | TAS1R3 (0.57) | ALDH1A1TAS1R3TAS1R1KDM4EGAA | |
| SCHEMBL1390698 | 0.80 | CA12 (0.50) | ALDH1A1TAS1R3TAS1R1LMNAKDM4E | |
| SCHEMBL1391068 | 0.77 | CA12 (0.53) | ALDH1A1TAS1R3TAS1R1KDM4EADAM17 | |
| SCHEMBL1390744 | 0.76 | KDM4E (0.43) | ALOX5ALDH1A1LMNAKDM4EGLA | |
| SCHEMBL19406000 | 0.75 | HIF1A (0.36) | ALOX5ALDH1A1USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |