SCHEMBL31301099

SCHEMBL31301099

CC(=O)N[C@H](C)c1cc2ccccc2o1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
LMNA P02545 2/20 0.54
THRB P10828 1/20 0.54
MAOB P27338 4/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
KDM4E B2RXH2 3/20 0.51
MAOA P21397 2/20 0.51
HPGD P15428 2/20 0.51
CYP1A2 P05177 2/20 0.51
HSD17B10 Q99714 2/20 0.51
POLB P06746 2/20 0.50
MAPT P10636 1/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
CYP2D6 P10635 1/20 0.48
HIF1A Q16665 1/20 0.48
TAS1R3 Q7RTX0 1/20 0.48
TAS1R1 Q7RTX1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4499439 1.00 ALDH1A1 (0.54) ALDH1A1LMNATHRBMAOBSMN1; SMN2
SCHEMBL9684715 0.84 ALDH1A1 (0.51) ALDH1A1LMNATHRBMAOBSMN1; SMN2
SCHEMBL9685852 0.82 ALDH1A1 (0.49) ALDH1A1LMNATHRBMAOBSMN1; SMN2
SCHEMBL1391086 0.81 KDM4E (0.54) ALDH1A1LMNAMAOBSMN1; SMN2KDM4E
SCHEMBL1391118 0.81 MIF (0.50) ALDH1A1LMNAKDM4EHPGDHSD17B10
SCHEMBL13601005 0.81 ALDH1A1 (0.48) ALDH1A1LMNATHRBMAOBSMN1; SMN2
SCHEMBL1390747 0.80 ALOX5 (0.37) ALDH1A1LMNATHRBMAOBSMN1; SMN2
SCHEMBL7920650 0.80 ALOX5 (0.37) ALDH1A1LMNATHRBSMN1; SMN2KDM4E
SCHEMBL1390756 0.80 HTT (0.54) ALDH1A1MAOACYP1A2MAPTMEN1
SCHEMBL28657395 0.80 MAOB (0.48) ALDH1A1LMNATHRBMAOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118995869-A Method for preparing (R) -N-acetyl-alpha-arylethylamine derivative by photocatalytic asymmetric reduction 南京大学 2024-11-22 CN disclosed