Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911928 | 0.90 | ALDH1A1 (0.50) | FABP4ALDH1A1L3MBTL1TSHRLMNA | |
| SCHEMBL7918986 | 0.84 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1TSHRLMNAHTT | |
| SCHEMBL7924070 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TSHRTBXA2RTBXAS1GAA | |
| SCHEMBL7919255 | 0.81 | PSEN1 (0.48) | ALDH1A1TSHRLMNAHTTTBXA2R | |
| SCHEMBL8438783 | 0.81 | L3MBTL1 (0.52) | FABP4ALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL7921068 | 0.80 | TBXA2R (0.67) | ALDH1A1TSHRHTTTBXA2RTBXAS1 | |
| SCHEMBL7918922 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNAHTTTBXA2R | |
| SCHEMBL7911845 | 0.78 | GRIN1 (0.47) | ALDH1A1TSHRLMNAHTTTBXA2R | |
| SCHEMBL7920702 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNAHTTTBXA2R | |
| SCHEMBL7919243 | 0.77 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1TSHRLMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5189211-A | Thromboxane A2 antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |