Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920576 | 0.88 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP3A4CYP2C9NFKB1 | |
| SCHEMBL7919267 | 0.85 | ALDH1A1 (0.65) | ALDH1A1TBXA2RTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL7921068 | 0.83 | TBXA2R (0.67) | ALDH1A1TBXA2RTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL7920711 | 0.83 | FABP4 (0.50) | ALDH1A1TBXA2RTBXAS1GAANPC1 | |
| SCHEMBL7918986 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TBXA2RTBXAS1CYP2C9GAA | |
| SCHEMBL7919243 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TBXA2RTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL7920702 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TBXA2RTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL7918922 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TBXA2RTBXAS1CYP2C9HSD17B10 | |
| SCHEMBL8441006 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TBXA2RTBXAS1CYP1A2CYP3A4 | |
| SCHEMBL7921083 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP3A4CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811375-B1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA LTD (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-0811375-A1 | GLUTAMIC ACID RECEPTOR AGONIST | NIPPON SUISAN KAISHA, LTD. (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0469901-B1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5189211-A | Thromboxane A2 antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0469901-A1 | Sulfonamide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-02-05 | — | — | EP | disclosed |