Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923807 | 0.89 | HTR7 (0.51) | KMOL3MBTL1HTR7 | |
| SCHEMBL7928062 | 0.85 | ALOX5 (0.47) | KRASPLGPLAUALOX5EPHX2 | |
| SCHEMBL6230447 | 0.84 | PLG (0.46) | KRASPLGPLAUHTR7 | |
| SCHEMBL14404541 | 0.83 | PLG (0.44) | KRASPLGPLAUHTR7 | |
| SCHEMBL10430002 | 0.83 | PLG (0.46) | KRASPLGPLAUHTR7 | |
| SCHEMBL3184801 | 0.82 | KRAS (0.55) | KRASPLGPLAU | |
| SCHEMBL23902730 | 0.81 | GLS (0.46) | KRASPLGPLAUHTR7 | |
| SCHEMBL2263041 | 0.81 | GLS (0.46) | KRASPLGPLAUHTR7 | |
| SCHEMBL30241520 | 0.81 | GLS (0.46) | KRASPLGPLAUHTR7 | |
| SCHEMBL2479169 | 0.81 | HTR7 (0.47) | KRASPLGPLAUHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239159-B1 | SUBSTRATES FOR POLYMERASE AND TERMINAL TRANSFERASE ENZYMES. CAPABLE OF BASE-PAIRING WITH A NUCLEOTIDE RESIDUE IN A COMPLEMENTARY CHAIN OR BASE STACKING IN THE APPROPRIATE NUCLEIC ACID CHAIN, ADVANTAGE OVER CONVENTIONAL HAPTEN | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2001-05-29 | — | — | US | disclosed |
| EP-0885235-A1 | NUCLEOSIDE ANALOGUES | Amersham Pharmacia Biotech UK Limited (GB) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997028176-A1 | NUCLEOSIDE ANALOGUES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |