Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545929 | 0.92 | KRAS (0.47) | ALOX5EPHX2KRASMTNR1AMTNR1B | |
| SCHEMBL9479096 | 0.90 | HTR7 (0.53) | ALOX5EPHX2MTNR1AMTNR1BHTR7 | |
| SCHEMBL7921048 | 0.85 | KRAS (0.47) | ALOX5EPHX2KRASHTR7PLG | |
| SCHEMBL14876295 | 0.84 | ATM (0.55) | KRASMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL2872712 | 0.82 | HTR7 (0.57) | MTNR1AMTNR1BHTR7MEN1KMT2A | |
| SCHEMBL10430002 | 0.81 | PLG (0.46) | KRASHTR7PLGPLAU | |
| SCHEMBL7085455 | 0.81 | MTNR1A (0.53) | MTNR1AMTNR1BHTR7MEN1KMT2A | |
| SCHEMBL6233916 | 0.81 | MEN1 (0.43) | KRASMEN1KMT2APLGPLAU | |
| SCHEMBL6230447 | 0.80 | PLG (0.46) | KRASHTR7MAPTPLGPLAU | |
| SCHEMBL7417377 | 0.80 | MAPT (0.49) | KRASMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239159-B1 | SUBSTRATES FOR POLYMERASE AND TERMINAL TRANSFERASE ENZYMES. CAPABLE OF BASE-PAIRING WITH A NUCLEOTIDE RESIDUE IN A COMPLEMENTARY CHAIN OR BASE STACKING IN THE APPROPRIATE NUCLEIC ACID CHAIN, ADVANTAGE OVER CONVENTIONAL HAPTEN | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2001-05-29 | — | — | US | disclosed |
| EP-0885235-A1 | NUCLEOSIDE ANALOGUES | Amersham Pharmacia Biotech UK Limited (GB) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997028176-A1 | NUCLEOSIDE ANALOGUES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |