Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10266218 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDTYRCTSB | |
| SCHEMBL22110048 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDTYRCTSB | |
| SCHEMBL10266220 | 0.89 | TYR (0.51) | ALDH1A1KDM4EHPGDTYRCTSB | |
| SCHEMBL3478854 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDTYRCTSB | |
| SCHEMBL11947493 | 0.89 | CTSB (0.46) | ALDH1A1KDM4EHPGDTYRCTSB | |
| SCHEMBL9892685 | 0.85 | TYR (0.40) | ALDH1A1KDM4ETYRCTSBPPP3CB | |
| SCHEMBL7898739 | 0.82 | MAPT (0.45) | ALDH1A1KDM4EHPGDTYRCTSB | |
| SCHEMBL7907810 | 0.81 | KCNQ1 (0.45) | ALDH1A1KDM4EHPGDTYRCTSB | |
| SCHEMBL7921060 | 0.78 | TYR (0.51) | ALDH1A1KDM4EHPGDTYRKMT2A | |
| SCHEMBL15766260 | 0.77 | TYR (0.46) | ALDH1A1KDM4EHPGDTYRCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142929-A1 | PROCESS FOR PREPARING SULFONYL QUINOLINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142929-A1 | PROCESS FOR PREPARING SULFONYL QUINOLINES | GYS2, CYP3A7, GBA1 | ALDH1A1 771/4885KDM4E 2420/4885HPGD 2942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.