Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139831 | 0.92 | LMNA (0.56) | LMNATSHRALDH1A1TP53MAPT | |
| SCHEMBL7923524 | 0.91 | LMNA (0.48) | LMNATSHRALDH1A1TP53MAPT | |
| SCHEMBL7927261 | 0.90 | LMNA (0.48) | LMNATSHRALDH1A1TP53MAPT | |
| SCHEMBL7927130 | 0.88 | MEN1 (0.54) | LMNATSHRALDH1A1TP53SIGMAR1 | |
| SCHEMBL7924072 | 0.87 | LMNA (0.50) | LMNATSHRALDH1A1TP53MAPT | |
| SCHEMBL7915448 | 0.87 | KDM4E (0.46) | LMNATSHRALDH1A1TP53MAPT | |
| SCHEMBL7923527 | 0.87 | TP53 (0.47) | LMNATSHRALDH1A1TP53USP2 | |
| SCHEMBL7923044 | 0.86 | LMNA (0.57) | LMNATSHRALDH1A1TP53USP2 | |
| SCHEMBL7915276 | 0.86 | LMNA (0.53) | LMNATSHRALDH1A1TP53MAPT | |
| SCHEMBL7921974 | 0.85 | CA12 (0.56) | LMNATSHRALDH1A1TP53USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |