Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139831 | 0.92 | LMNA (0.56) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7915276 | 0.91 | LMNA (0.53) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921093 | 0.90 | LMNA (0.48) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7923524 | 0.90 | LMNA (0.48) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921905 | 0.89 | LMNA (0.46) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7921616 | 0.87 | LMNA (0.44) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7923296 | 0.87 | LMNA (0.47) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7924072 | 0.86 | LMNA (0.50) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL7927130 | 0.85 | MEN1 (0.54) | LMNAALDH1A1TSHRTP53MEN1 | |
| SCHEMBL7921974 | 0.84 | CA12 (0.56) | LMNAALDH1A1TSHRTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |