Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923519 | 0.89 | LMNA (0.61) | LMNAMAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL7923296 | 0.89 | LMNA (0.47) | LMNAUSP2THRBMAPTTSHR | |
| SCHEMBL7923527 | 0.88 | TP53 (0.47) | LMNAUSP2THRBMAPTTSHR | |
| SCHEMBL7921093 | 0.86 | LMNA (0.48) | LMNAUSP2THRBMAPTTSHR | |
| SCHEMBL7921975 | 0.86 | ALDH1A1 (0.60) | LMNAMAPTTSHRALDH1A1KCNH2 | |
| SCHEMBL7927315 | 0.84 | KDM4E (0.58) | LMNAMAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL7924133 | 0.84 | LMNA (0.48) | LMNAMAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL7927267 | 0.84 | MAPT (0.49) | LMNAUSP2MAPTTSHRKDM4E | |
| SCHEMBL7924162 | 0.83 | KDM4E (0.62) | LMNAMAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL7921522 | 0.82 | KMT2A (0.56) | LMNAMAPTTSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |