Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528973 | 0.85 | PLK1 (1.00) | PLK1NPC1RAB9ANPSR1HPGD | |
| SCHEMBL28912681 | 0.84 | PLK1 (0.72) | PLK1NPC1RAB9ANPSR1HPGD | |
| SCHEMBL28467015 | 0.83 | KMT2A (0.56) | PLK1NPC1RAB9ANPSR1HPGD | |
| SCHEMBL7915934 | 0.83 | MAPT (0.59) | PLK1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7921183 | 0.83 | TBXAS1 (0.58) | PLK1NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL14880157 | 0.81 | PLK1 (0.73) | PLK1NPC1RAB9ANPSR1HPGD | |
| SCHEMBL2636457 | 0.81 | PLK1 (0.73) | PLK1NPC1RAB9ANPSR1HPGD | |
| SCHEMBL1406507 | 0.81 | PLK1 (0.68) | PLK1NPC1RAB9ANPSR1HPGD | |
| SCHEMBL15482198 | 0.80 | HDAC6 (0.52) | PLK1HPGDKMT2ALMNAMEN1 | |
| SCHEMBL10294638 | 0.80 | RAB9A (0.75) | PLK1NPC1RAB9ANPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048340-A2 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |