Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915934 | 0.87 | MAPT (0.59) | TBXAS1PLK1SMN1; SMN2KDM4EHTT | |
| SCHEMBL4751615 | 0.86 | PLK1 (0.75) | TBXAS1PLK1SMN1; SMN2HTTGAA | |
| SCHEMBL7921171 | 0.83 | PLK1 (0.74) | PLK1SMN1; SMN2KDM4EHTTL3MBTL1 | |
| SCHEMBL20424310 | 0.81 | GAA (0.59) | PLK1GAANR1I2NPC1MAPT | |
| SCHEMBL78852 | 0.80 | L3MBTL1 (0.78) | GAANR1I2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL7916855 | 0.80 | PLK1 (0.57) | TBXAS1PLK1SMN1; SMN2KDM4EHTT | |
| SCHEMBL17431019 | 0.79 | AOC3 (0.56) | PLK1SMN1; SMN2HTTGAANR1I2 | |
| SCHEMBL5180990 | 0.78 | MAPT (0.64) | SMN1; SMN2KDM4EGAANPC1MAPT | |
| SCHEMBL18914860 | 0.78 | PLK1 (0.73) | TBXAS1PLK1SMN1; SMN2HTTGAA | |
| SCHEMBL22192224 | 0.78 | MAPT (0.64) | SMN1; SMN2KDM4EGAANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048340-A2 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |