Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921183 | 0.87 | TBXAS1 (0.58) | MAPTTBXAS1PLK1KDM4EHTT | |
| SCHEMBL4751488 | 0.86 | PLK1 (0.75) | MAPTTBXAS1PLK1HTTSMN1; SMN2 | |
| SCHEMBL7921171 | 0.83 | PLK1 (0.74) | MAPTPLK1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL13678971 | 0.83 | MAPT (0.54) | MAPTPLK1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL933535 | 0.82 | L3MBTL1 (0.75) | MAPTRAB9AL3MBTL1GAAALDH1A1 | |
| SCHEMBL386165 | 0.81 | MAPT (0.89) | MAPTPLK1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL13108708 | 0.80 | MAPT (0.63) | MAPTPLK1RAB9AL3MBTL1NPC1 | |
| SCHEMBL7915810 | 0.80 | PLK1 (0.71) | MAPTPLK1HTTSMN1; SMN2RAB9A | |
| SCHEMBL12455672 | 0.80 | MAPT (0.63) | MAPTPLK1RAB9AL3MBTL1NPC1 | |
| SCHEMBL7916855 | 0.80 | PLK1 (0.57) | MAPTTBXAS1PLK1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048340-A2 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |