Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | SELE | P16581 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919799 | 0.85 | PTGES (0.60) | GAAPTGESTBXA2RALDH1A1MAPT | |
| SCHEMBL18585000 | 0.84 | KMT2A (0.52) | GAAALDH1A1MAPTLMNAHSD17B10 | |
| SCHEMBL18641503 | 0.84 | MAPT (0.46) | GAAPTGESALDH1A1MAPTLMNA | |
| SCHEMBL2954723 | 0.80 | SMN1; SMN2 (0.58) | ALDH1A1MAPTLMNAHSD17B10HPGD | |
| SCHEMBL6935214 | 0.80 | GAA (0.46) | GAAPTGESTBXA2RALDH1A1MAPT | |
| SCHEMBL6756967 | 0.80 | POLB (0.52) | GAAPTGESTBXA2RALDH1A1MAPT | |
| SCHEMBL18585210 | 0.78 | MAPT (0.39) | GAAPTGESALDH1A1MAPTLMNA | |
| SCHEMBL1163261 | 0.76 | ADRB2 (0.56) | GAAALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL18641436 | 0.76 | MAPT (0.49) | GAAPTGESTBXA2RALDH1A1MAPT | |
| SCHEMBL1403472 | 0.76 | ALDH1A1 (0.56) | GAAALDH1A1MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291442-B1 | Pharmacological modulators of voltage-gated potassium ion channels | THE GENERAL HOSPITAL CORPORATION | 2001-09-18 | — | — | US | disclosed |