SCHEMBL79216

SCHEMBL79216

O=S(=O)(n1ccnc1)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.48
▸ TP53 P04637 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ LMNA P02545 3/20 0.38
▸ FABP4 P15090 1/20 0.37
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ FDPS P14324 2/20 0.32
▸ ALDH1A1 P00352 3/20 0.31
▸ HSD17B10 Q99714 2/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ QPCT Q16769 1/20 0.31
▸ QPCTL Q9NXS2 1/20 0.31
▸ GGPS1 O95749 2/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL29254073 0.92 HTT (0.43) HTTTP53TSHRLMNAFABP4
SCHEMBL28875492 0.78 HTT (0.53) HTTTP53TSHRLMNAFABP4
Trifluoromethanesulfonic Acid SCHEMBL26908180 0.76 HTT (0.43) HTTTP53TSHRLMNAFABP4
SCHEMBL21034076 0.75 — —
SCHEMBL6300741 0.74 HTT (0.58) HTTTP53TSHRLMNAFABP4
SCHEMBL1157477 0.74 HTT (0.58) HTTTP53TSHRLMNAFABP4
SCHEMBL25091130 0.74 HTT (0.44) HTTTP53TSHRLMNAFABP4
SCHEMBL31191350 0.74 HTT (0.58) HTTTP53TSHRLMNAFABP4
SCHEMBL31191271 0.74 HTT (0.44) HTTTP53TSHRLMNAFABP4
SCHEMBL27744132 0.74 HTT (0.44) HTTTP53TSHRLMNAFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658652-A2 PROCESSES AND INTERMEDIATES FOR SYNTHESIS OF ADAGRASIB Mirati Therapeutics, Inc. (US) 2025-12-10 — — EP claimed
EP-4090654-B1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LTD (IN) 2025-07-09 — — EP claimed
US-12344592-B2 Methods, processes and intermediates for preparing chroman compounds LUPIN LIMITED (IN) 2025-07-01 — — US claimed
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same THE GEORGE WASHINGTON UNIVERSITY (US) 2025-01-14 — — US claimed
WO-2024163626-A2 PROCESSES AND INTERMEDIATES FOR SYNTHESIS OF ADAGRASIB Mirati Therapeutics, Inc. (US) 2024-08-08 — — WO claimed
US-20240254066-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2024-08-01 — — US claimed
CN-114981253-B Process and intermediates for preparing chroman compounds and methods therefor 印度鲁宾有限公司 2024-06-18 — — CN claimed
EP-4337315-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF GW Research Limited (GB) 2024-03-20 — — EP claimed
CN-117396455-A Resorcinol, its manufacturing method and use 吉伟研究有限公司 2024-01-12 — — CN claimed
US-20230140054-A1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LIMITED (IN) 2023-05-04 — — US claimed
EP-4090654-A1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS Lupin Limited (IN) 2022-11-23 — — EP claimed
WO-2022238707-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF GW Research Limited (GB) 2022-11-17 — — WO claimed
CN-114981253-A Process and intermediates for preparing chroman compounds and methods therefor 印度鲁宾有限公司 2022-08-30 — — CN claimed
WO-2021144814-A1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LIMITED (IN) 2021-07-22 — — WO claimed
US-20200171474-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME THE GEORGE WASHINGTON UNIVERSITY 2020-06-04 — — US claimed
EP-3509988-A1 MULTI-DOPED GRAPHENE AND METHOD FOR PREPARING THE SAME LG Electronics Inc. -1- (KR) 2019-07-17 — — EP claimed
WO-2018213821-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME THE GEORGE WASHINGTON UNIVERSITY (US) 2018-11-22 — — WO claimed
WO-2018048059-A1 MULTI-DOPED GRAPHENE AND METHOD FOR PREPARING THE SAME LG ELECTRONICS INC. (KR) 2018-03-15 — — WO claimed
US-20180069082-A1 MULTI-DOPED GRAPHENE AND METHOD FOR PREPARING THE SAME LG ELECTRONICS INC. (KR) 2018-03-08 — — US claimed
US-20140031289-A1 POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-01-30 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230140054-A1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS CASR, CALCR, RYR1 HTT 4148/4885TP53 3386/4885TSHR 261/4885
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same MLX, LDHA, CA2 HTT 1471/4885TP53 2528/4885TSHR 2120/4885
US-20140031289-A1 POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF PHOSPHO1, PLCB3, INPP5D HTT 4685/4885TP53 2697/4885TSHR 3450/4885
US-20200171474-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME MLX, LDHA, CA2 HTT 1471/4885TP53 2528/4885TSHR 2120/4885
US-20240254066-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF REN, CYP46A1, NQO1 HTT 45/4885TP53 3347/4885TSHR 4147/4885
US-12344592-B2 Methods, processes and intermediates for preparing chroman compounds CASR, CALCR, RYR1 HTT 4148/4885TP53 3386/4885TSHR 261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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