Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921905 | 0.92 | LMNA (0.46) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7921580 | 0.90 | LMNA (0.45) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7923527 | 0.90 | TP53 (0.47) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7915565 | 0.89 | LMNA (0.56) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7923296 | 0.88 | LMNA (0.47) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7927261 | 0.87 | LMNA (0.48) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7924033 | 0.85 | LMNA (0.44) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7915494 | 0.84 | LMNA (0.45) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7921529 | 0.84 | LMNA (0.55) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7921923 | 0.83 | LMNA (0.58) | LMNAALDH1A1TSHRMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |