Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921905 | 0.90 | LMNA (0.46) | LMNAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL7923044 | 0.89 | LMNA (0.57) | LMNAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL7921616 | 0.88 | LMNA (0.44) | LMNAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL7923519 | 0.88 | LMNA (0.61) | LMNAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL7927261 | 0.87 | LMNA (0.48) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7921923 | 0.86 | LMNA (0.58) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7927267 | 0.83 | MAPT (0.49) | LMNAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL7924133 | 0.83 | LMNA (0.48) | LMNAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL7924162 | 0.82 | KDM4E (0.62) | LMNAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL6139516 | 0.80 | KDM4E (0.60) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |