Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927884 | 0.84 | ALDH1A1 (0.41) | PDK1NLRP3ALDH1A1LMNACYP3A4 | |
| SCHEMBL5013481 | 0.75 | — | — | |
| SCHEMBL11205236 | 0.74 | PDK1 (0.42) | PDK1NLRP3ALDH1A1LMNAPOLB | |
| SCHEMBL260743 | 0.74 | NLRP3 (0.36) | PDK1NLRP3ALDH1A1LMNACYP3A4 | |
| SCHEMBL259449 | 0.74 | NLRP3 (0.36) | PDK1NLRP3ALDH1A1LMNACYP3A4 | |
| SCHEMBL11640211 | 0.71 | NLRP3 (0.38) | PDK1NLRP3ALDH1A1LMNACYP3A4 | |
| SCHEMBL10290385 | 0.70 | LMNA (0.64) | PDK1ALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL17269992 | 0.70 | LMNA (0.64) | PDK1ALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL118897 | 0.70 | LMNA (0.64) | PDK1ALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL29983676 | 0.70 | PDK1 (0.39) | PDK1NLRP3ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | KLINTZ RALF (DE) | 2001-10-18 | — | — | US | disclosed |
| US-6239074-B1 | HERBICIDES, INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-29 | — | — | US | disclosed |
| EP-0604491-A1 | SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1994-07-06 | — | — | EP | disclosed |
| WO-1993006090-A1 | SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031865-A1 | Substituted 3-phenyluracils | CCR1, CCR6, CCR3 | PDK1 3545/4885NLRP3 3892/4885ALDH1A1 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.