Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921747 | 0.90 | LMNA (0.62) | LMNAMAPTALDH1A1TSHRTP53 | |
| SCHEMBL7921621 | 0.90 | ALDH1A1 (0.76) | LMNAMAPTALDH1A1TSHRTP53 | |
| SCHEMBL7921923 | 0.89 | LMNA (0.58) | LMNAMAPTALDH1A1TSHRTP53 | |
| SCHEMBL7594639 | 0.89 | LMNA (0.61) | LMNAMAPTALDH1A1TSHRTP53 | |
| SCHEMBL7921776 | 0.87 | LMNA (0.58) | LMNAMAPTALDH1A1TSHRTP53 | |
| SCHEMBL7927377 | 0.85 | LMNA (0.56) | LMNAMAPTALDH1A1TSHRTP53 | |
| SCHEMBL7923483 | 0.84 | LMNA (0.56) | LMNAMAPTALDH1A1TSHRTP53 | |
| SCHEMBL7921975 | 0.83 | ALDH1A1 (0.60) | LMNAMAPTALDH1A1TSHRTP53 | |
| SCHEMBL7921838 | 0.83 | LMNA (0.60) | LMNAMAPTALDH1A1TSHRTP53 | |
| SCHEMBL7923135 | 0.83 | LMNA (0.57) | LMNAMAPTALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |