Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927355 | 0.96 | DRD2 (0.46) | DRD2MAPTLMNAHTTTDP1 | |
| SCHEMBL7915494 | 0.90 | LMNA (0.45) | DRD2MAPTLMNAHTTALDH1A1 | |
| SCHEMBL7927267 | 0.90 | MAPT (0.49) | MAPTLMNAHTTTDP1ALDH1A1 | |
| SCHEMBL7915565 | 0.89 | LMNA (0.56) | DRD2MAPTLMNAHTTALDH1A1 | |
| SCHEMBL7923972 | 0.87 | LMNA (0.44) | DRD2MAPTLMNAHTTALDH1A1 | |
| SCHEMBL7921529 | 0.86 | LMNA (0.55) | MAPTLMNAALDH1A1TSHRTP53 | |
| SCHEMBL7923508 | 0.86 | MEN1 (0.44) | MAPTLMNAHTTALDH1A1TSHR | |
| SCHEMBL7921974 | 0.86 | CA12 (0.56) | MAPTLMNATDP1ALDH1A1TSHR | |
| SCHEMBL7927375 | 0.84 | KDM4E (0.54) | DRD2MAPTLMNAHTTTDP1 | |
| SCHEMBL7921580 | 0.83 | LMNA (0.45) | DRD2MAPTLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |