Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915494 | 0.95 | LMNA (0.45) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7927355 | 0.91 | DRD2 (0.46) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7921529 | 0.91 | LMNA (0.55) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7923493 | 0.91 | LMNA (0.47) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7924033 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7915519 | 0.88 | HTR1A (0.44) | LMNAALDH1A1TSHRMAPTHTT | |
| SCHEMBL7923469 | 0.87 | IGF1R (0.41) | LMNAALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL7921790 | 0.87 | DRD2 (0.46) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7924133 | 0.86 | LMNA (0.48) | LMNAALDH1A1TSHRMAPTTP53 | |
| SCHEMBL7915565 | 0.86 | LMNA (0.56) | LMNAALDH1A1TSHRMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |