Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991714 | 0.82 | GABRA1 (0.34) | CYP2C19ALDH1A1CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL6407060 | 0.81 | MAPT (0.42) | CYP2C19KLF10ALDH1A1GAAXBP1 | |
| SCHEMBL7924644 | 0.76 | RXRA (0.32) | RARGRXRAPPARG | |
| SCHEMBL4677041 | 0.75 | CA2 (0.38) | ALDH1A1GAATSHRGABRA1GABRB2 | |
| SCHEMBL938679 | 0.72 | ALDH1A1 (0.49) | CYP2C19KLF10ALDH1A1GAAXBP1 | |
| SCHEMBL29577789 | 0.72 | ALDH1A1 (0.49) | CYP2C19KLF10ALDH1A1GAAXBP1 | |
| SCHEMBL7195524 | 0.71 | RARG (0.32) | RARGRXRAPPARG | |
| SCHEMBL7924691 | 0.71 | RXRA (0.40) | ALDH1A1GAANPSR1RARGRXRA | |
| SCHEMBL17594500 | 0.70 | CYP2C19 (0.39) | CYP2C19KLF10ALDH1A1GAAXBP1 | |
| SCHEMBL12929955 | 0.69 | MAPT (0.43) | CYP2C19KLF10ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232430-B1 | PYRROLIDIN-2,5-DIONE COMPOUND | JDS UNIPHASE PHOTONICS C.V. (NL) | 2001-05-15 | — | — | US | disclosed |
| EP-0934266-A1 | CROSS-LINKERS FOR CROSS-LINKABLE OPTICAL POLYCARBONATES | Akzo Nobel N.V. (NL) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017644-A1 | CROSS-LINKERS FOR CROSS-LINKABLE OPTICAL POLYCARBONATES | AKZO NOBEL N.V. (NL) | 1998-04-30 | — | — | WO | disclosed |