SCHEMBL7922365

SCHEMBL7922365

CCc1ccc(C(C)(c2ccc(O)cc2)c2ccc(O)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
ESR1 P03372 14/20 0.59
ESR2 Q92731 12/20 0.59
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
APAF1 O14727 1/20 0.50
USP2 O75604 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50
MAPK1 P28482 1/20 0.50
CASP1 P29466 1/20 0.50
BLM P54132 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10772514 0.94 MEN1 (0.58) MEN1KMT2AESR1ESR2HPGD
SCHEMBL27879524 0.87 LMNA (0.70) MEN1KMT2AESR1ESR2HPGD
SCHEMBL27833259 0.87 ESR1 (0.70) MEN1KMT2AESR1ESR2HPGD
SCHEMBL3649608 0.84 MEN1 (0.66) MEN1KMT2AESR1ESR2HPGD
SCHEMBL18750 0.83 ESR1 (0.80) MEN1KMT2AESR1ESR2HPGD
SCHEMBL22335854 0.83 ESR1 (0.80) MEN1KMT2AESR1ESR2HPGD
SCHEMBL28148524 0.83 ALDH1A1 (0.64) MEN1KMT2AESR1ESR2HPGD
SCHEMBL4063477 0.83 ESR1 (0.80) MEN1KMT2AESR1ESR2HPGD
SCHEMBL28713 0.83
SCHEMBL7917092 0.83 MEN1 (0.70) MEN1KMT2AESR1ESR2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6217995-B1 TRANSPARENT POLYCARBONATE OR POLYESTERCARABONATE CONTAINING CYCLIC ALIPHATIC GROUP, HAVING A VISIBLE LIGHT TRANSMITTANCE MORE THAN 80% AND A GLASS TRANSITION TEMPERATURE LESS THAN 80 DEGREE C. EXHIBIT BIREFRINGENCE INDEX LESS THAN 15 NM MITSUBISHI CHEMICAL CORPORATION (JP) 2001-04-17 US disclosed
US-5138001-A Optical disc substrates; low birefringence, heat and moisture absorption resistance, high transparency TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1992-08-11 US disclosed
EP-0415729-A2 Vinylphenyl compound, process for the production thereof, polymerizable composition containing same, and crosslinked polymer formed therefrom TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed