Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932591 | 0.89 | MMP12 (0.63) | MMP12MMP13MMP2MMP3GRIK1 | |
| SCHEMBL1862879 | 0.89 | PRSS1 (0.47) | MMP12MMP13MMP2MMP3GRIK1 | |
| SCHEMBL7928277 | 0.88 | MMP12 (0.64) | MMP12MMP13MMP2MMP3GRIK1 | |
| SCHEMBL1861903 | 0.87 | GRIK1 (0.59) | MMP12MMP13MMP2MMP3GRIK1 | |
| SCHEMBL3466543 | 0.87 | MMP12 (0.51) | MMP12MMP13MMP2MMP3PRSS1 | |
| SCHEMBL7924568 | 0.86 | MMP12 (0.48) | MMP12MMP13MMP2MMP3PRSS1 | |
| SCHEMBL3466957 | 0.84 | FFAR1 (0.51) | MMP2MMP3GRIK1MMEFAAH | |
| SCHEMBL1860416 | 0.83 | GRIK1 (0.68) | MMP2MMP3GRIK1FOLH1 | |
| SCHEMBL7922577 | 0.82 | PPARG (0.56) | MMP12MMP13MMP2MMP3GRIK1 | |
| SCHEMBL7924101 | 0.82 | GRIK1 (0.54) | MMP12MMP13MMP2MMP3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |