Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917889 | 0.92 | MMP12 (0.55) | MMP12MMP13MMP3MMP2FFAR1 | |
| SCHEMBL7922593 | 0.86 | MMP12 (0.56) | MMP12MMP13MMP3MMP2FOLH1 | |
| SCHEMBL1858161 | 0.85 | KMT2A (0.52) | FFAR1AKR1B1KMT2ASIGMAR1MCL1 | |
| SCHEMBL7929539 | 0.83 | MMP2 (0.48) | MMP3MMP2FFAR1AKR1B1KMT2A | |
| SCHEMBL7926499 | 0.83 | PTPN1 (0.53) | MMP3MMP2FFAR1AKR1B1KMT2A | |
| SCHEMBL1862472 | 0.82 | KMT2A (0.47) | MMP3MMP2FFAR1AKR1B1KMT2A | |
| SCHEMBL1859538 | 0.81 | MMP12 (0.47) | MMP12MMP3MMP2 | |
| SCHEMBL1857173 | 0.80 | MMP2 (0.42) | MMP3MMP2FFAR1AKR1B1KMT2A | |
| SCHEMBL7928277 | 0.80 | MMP12 (0.64) | MMP12MMP13MMP3MMP2FFAR1 | |
| SCHEMBL3469955 | 0.79 | SLC13A5 (0.46) | MMP3MMP2AKR1B1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |