Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127592 | 0.78 | HSD11B1 (0.43) | ALDH1A1MAPTLMNAHSD11B1L3MBTL1 | |
| SCHEMBL1072567 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHSD11B1L3MBTL1 | |
| SCHEMBL10616048 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAHSD11B1L3MBTL1 | |
| SCHEMBL27724281 | 0.72 | HSD11B1 (0.46) | ALDH1A1HSD11B1L3MBTL1HTTCRHBP | |
| SCHEMBL7734591 | 0.71 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAHSD11B1L3MBTL1 | |
| SCHEMBL1607368 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHTTCRHBP | |
| SCHEMBL251840 | 0.71 | HSD11B1 (0.50) | ALDH1A1MAPTLMNAHSD11B1L3MBTL1 | |
| Potassium SCHEMBL31135095 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAHTTCRHBP | |
| SCHEMBL133056 | 0.69 | HSD11B1 (0.48) | ALDH1A1MAPTLMNAHSD11B1L3MBTL1 | |
| SCHEMBL546352 | 0.69 | HTT (0.48) | ALDH1A1MAPTLMNAHSD11B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010032129-A1 | METHOD FOR PRODUCING ADAMANTYL COMPOUNDS | FINORGA (FR) | 2010-03-25 | — | — | WO | disclosed |