SCHEMBL7922622

SCHEMBL7922622

CCOc1c(Br)c(Br)c(Br)c(Br)c1Br

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 1/20 0.37
NQO1 P15559 1/20 0.36
CA2 P00918 2/20 0.35
CA4 P22748 2/20 0.35
CA1 P00915 1/20 0.35
CA6 P23280 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
TSHR P16473 2/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4885551 0.83 LMNA (0.32) THRBLMNA
SCHEMBL4889126 0.82 LMNA (0.34) THRBSMN1; SMN2HPGDLMNA
SCHEMBL10415131 0.78 THRB (0.37) THRBSMN1; SMN2HPGDNQO1CA2
SCHEMBL94853 0.73 CA1 (0.32) CA2CA4CA1CA6
SCHEMBL11640450 0.73 CA1 (0.32) CA2CA4CA1CA6
SCHEMBL21869919 0.73
SCHEMBL28266815 0.73 THRB (0.33) THRBSMN1; SMN2HPGDNQO1ALDH1A1
SCHEMBL11407591 0.73 THRA (0.46) THRBSMN1; SMN2CA2CA1ALDH1A1
Alcohol SCHEMBL11043389 0.71 ALDH1A1 (0.40) THRBCA2CA4ALDH1A1TSHR
SCHEMBL2290336 0.71 THRA (0.47) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4945018-A WIRE AND CABLE INSULATION, PHOSPHATE OR PHOSPHONATE COMPOUND GENERAL ELECTRIC COMPANY (US) 1990-07-31 US claimed
EP-0129825-B1 MODIFIED BLENDS OF POLYPHENYLENE ETHER RESIN AND A POLYAMIDE GENERAL ELECTRIC COMPANY (US) 1988-09-21 EP claimed
US-4552911-A TETRAHALOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-12 US claimed
EP-0129824-A1 Flame retardant blends of ABS resin and polyphenylene ether GENERAL ELECTRIC COMPANY (US) 1985-01-02 EP claimed
EP-0086353-A1 Polycarbonate moulding compounds with flame resistance BAYER AG (DE) 1983-08-24 EP claimed
US-4072652-A POLYETHYLENE, BIS-(BROMO-SUBSTITUTED PHENOXY) ALKANES VELSICOL CHEMICAL CORPORATION (US) 1978-02-07 US claimed
EP-4724537-A1 COATING RESISTANT TO BIOGROWTH PARTICULARLY IN MARINE ENVIRONMENTS Core Industries II, LLC (US) 2026-04-15 EP disclosed
US-20240409755-A1 COATING RESISTANT TO BIOGROWTH PARTICULARLY IN MARINE ENVIRONMENTS CORE INDUSTRIES II, LLC 2024-12-12 US disclosed
WO-2024254171-A1 COATING RESISTANT TO BIOGROWTH PARTICULARLY IN MARINE ENVIRONMENTS CORE INDUSTRIES II, LLC (US) 2024-12-12 WO disclosed
CN-117624906-A Self-adhesive silicon rubber insulating strip and preparation method thereof 上海中垒电气材料有限公司 2024-03-01 CN disclosed
CN-115821584-A High-heat-insulation flame-retardant fiber yarn and preparation method thereof, and high-heat-insulation flame-retardant sun-shading fabric and preparation method thereof 宁波先锋新材料股份有限公司 2023-03-21 CN disclosed
CN-115443313-A Coloring agent, master batch containing coloring agent, coloring resin composition and molded object 东方化学工业株式会社 2022-12-06 CN disclosed
CN-113956384-A Preparation method of efficient flame-retardant polystyrene resin 南京越升挤出机械有限公司 2022-01-21 CN disclosed
EP-0779338-B1 Liquid crystalline resin compound and moldings thereof TORAY INDUSTRIES (JP) 2001-10-24 EP disclosed
US-5804634-A PARTIALLY AROMATIC LIQUID CRYSTALLINE POLYESTER, WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER, INORGANIC FILLER TORAY INDUSTRIES, INC. (JP) 1998-09-08 US disclosed
EP-0779338-A2 Liquid crystalline resin compound and moldings thereof TORAY INDUSTRIES, INC. (JP) 1997-06-18 EP disclosed
US-4552911-A TETRAHALOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-12 US disclosed
US-4496681-A BLEND OF STAR POLYMER OF STYRENE AND ALKA DIENE, BNROMINATED PHENYETHER ANTIMONY TRIXODDE, WITH MALEICANHYDRIDE-STYRENE COPOLYMER ATLANTIC RICHFIELD COMPANY (US) 1985-01-29 US disclosed
US-4268429-A Novel flame retardant polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1981-05-19 US disclosed
US-4207402-A STYRENE POLYMERS AND COPOLYMERS MONSANTO COMPANY (US) 1980-06-10 US disclosed