Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922259 | 0.88 | TASP1 (0.61) | TASP1MAPTTP53HPGDNPC1 | |
| SCHEMBL7920494 | 0.87 | TASP1 (0.56) | TASP1MAPTTP53HPGDNPC1 | |
| SCHEMBL7922258 | 0.85 | MAPT (0.48) | TASP1MAPTTP53HPGDNPC1 | |
| SCHEMBL10069515 | 0.84 | TASP1 (0.85) | TASP1MAPTTP53HPGDNPC1 | |
| SCHEMBL7920537 | 0.77 | MAPT (0.46) | TASP1MAPTTP53HPGDNPC1 | |
| SCHEMBL10068891 | 0.76 | TASP1 (1.00) | TASP1MAPTTP53HPGDNPC1 | |
| SCHEMBL14096399 | 0.72 | TASP1 (0.64) | TASP1MAPTTP53HPGDNPC1 | |
| SCHEMBL14096381 | 0.71 | TASP1 (0.60) | TASP1MAPTTP53HPGDNPC1 | |
| SCHEMBL7922641 | 0.70 | MAPT (0.61) | MAPTTP53MEN1KMT2AMAPK1 | |
| SCHEMBL1062494 | 0.69 | TASP1 (0.48) | TASP1MAPTTP53HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100500-A1 | THE USE OF CD4-BINDING SMALL MOLECULES TO INHIBIT HIV INFECTION | THOMAS JEFFERSON UNIVERSITY (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000004903-A1 | THE USE OF CD4-BINDING SMALL MOLECULES TO INHIBIT HIV INFECTION | THOMAS JEFFERSON UNIVERSITY (US) | 2000-02-03 | — | — | WO | claimed |