⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932082 | 0.82 | LMNA (0.31) | — | |
| SCHEMBL825745 | 0.77 | CES2 (0.46) | — | |
| SCHEMBL18242162 | 0.74 | — | — | |
| SCHEMBL1119444 | 0.72 | ESR1 (0.33) | — | |
| SCHEMBL16957735 | 0.67 | GABRB2 (0.42) | — | |
| SCHEMBL9000007 | 0.65 | TSHR (0.35) | — | |
| SCHEMBL19356883 | 0.65 | — | — | |
| SCHEMBL18242081 | 0.64 | — | — | |
| SCHEMBL18378280 | 0.64 | AR (0.31) | — | |
| SCHEMBL18241923 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791607-B1 | Substituted metallocene catalyst for the (co)polymerization of olefins | ENICHEM SPA (IT) | 2001-05-02 | — | — | EP | disclosed |
| US-5936051-A | FORMING POLYMERS OF HIGH MOLECULAR WEIGHT; CHEMICAL AND HEAT RESISTANCE; ALUMOXANE COCATALYSTS | ENICHEM S.P.A. (IT) | 1999-08-10 | — | — | US | disclosed |
| EP-0791607-A2 | Substituted metallocene catalyst for the (co)polymerization of olefins | ENICHEM S.p.A. (IT) | 1997-08-27 | — | — | EP | disclosed |