SCHEMBL7923375

SCHEMBL7923375

Cc1cc(C)c(CCc2ccccc2)cc1C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.42
MAOB P27338 4/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HTR1A P08908 1/20 0.41
DRD2 P14416 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KCNH2 Q12809 1/20 0.41
TAAR1 Q96RJ0 3/20 0.40
ATM Q13315 1/20 0.40
ABCB1 P08183 1/20 0.40
CYP2A6 P11509 1/20 0.39
HTR2A P28223 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11203789 0.81 MAOA (0.45) MAOAMAOBHTR1ADRD2ALOX15
SCHEMBL3199545 0.81 NPSR1 (0.50) NPSR1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL29737291 0.81 NPSR1 (0.50) NPSR1ALDH1A1HPGDALOX15HSD17B10
SCHEMBL11748855 0.80 BCL2 (0.50) ALDH1A1HPGDALOX15HSD17B10HTR2A
SCHEMBL16386796 0.80 L3MBTL1 (0.44) ALDH1A1HPGDKCNH2ATMSMN1; SMN2
SCHEMBL30173450 0.79 RAB9A (0.45) ALDH1A1ALOX12SMN1; SMN2
SCHEMBL26135708 0.79 MAOA (0.39) MAOAMAOBHTR1ADRD2ALDH1A1
SCHEMBL115910 0.79 RAB9A (0.45) ALDH1A1ALOX12SMN1; SMN2
SCHEMBL16191236 0.79 TAAR1 (0.57) ALDH1A1ALOX12TAAR1SMN1; SMN2
SCHEMBL11806673 0.79 TRAP1 (0.56) ABCB1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6215035-B1 LIQUID PHASE REACTION USING SOLID GALLIUM CATALYST COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2001-04-10 US disclosed