Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924027 | 0.84 | LMNA (0.48) | SMN1; SMN2NPSR1MAPTKDM4EMEN1 | |
| SCHEMBL7924018 | 0.81 | ALDH1A1 (0.58) | NPSR1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7915568 | 0.81 | CACNA2D1 (0.42) | SMN1; SMN2NPSR1MAPTMEN1CYP2D6 | |
| SCHEMBL7921597 | 0.79 | LMNA (0.55) | SMN1; SMN2NPSR1MAPTKDM4ETSHR | |
| SCHEMBL7922874 | 0.79 | MAPT (0.44) | SMN1; SMN2NPSR1MAPTKDM4EMEN1 | |
| SCHEMBL7921443 | 0.76 | ATM (0.45) | MEN1CYP2D6CYP2C19KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL7921978 | 0.76 | MEN1 (0.44) | SMN1; SMN2MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL7921763 | 0.76 | LMNA (0.56) | NPSR1MAPTMEN1KMT2ATSHR | |
| SCHEMBL195024 | 0.76 | LMNA (0.48) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7921655 | 0.75 | LMNA (0.48) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0995741-A1 | REMEDIES/PREVENTIVES FOR FREQUENT URINATION/URINARY INCONTINENCE AND TROPONE DERIVATIVES | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-04-26 | — | — | EP | disclosed |