Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921443 | 0.91 | ATM (0.45) | DRD2DRD3CYP3A4CHRM2ADRA2A | |
| Hydrochloric Acid SCHEMBL7921978 | 0.90 | MEN1 (0.44) | CYP3A4KCNH2USP2CYP1A2CYP2D6 | |
| SCHEMBL195024 | 0.86 | LMNA (0.48) | CACNA1BPOLBMAPTDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7921655 | 0.85 | LMNA (0.48) | CACNA1BPOLBMAPTDRD2DRD3 | |
| SCHEMBL7921250 | 0.84 | CACNA1B (0.42) | CACNA2D1CACNA1BCACNB1CACNA1CCACNA1G | |
| SCHEMBL7924056 | 0.82 | DRD2 (0.43) | CACNA1BMAPTDRD2DRD3CHRM2 | |
| SCHEMBL7923980 | 0.81 | SMN1; SMN2 (0.38) | MAPTNPSR1DRD2DRD4CYP2D6 | |
| SCHEMBL7921833 | 0.80 | TACR1 (0.38) | POLBMAPTCYP3A4KCNH2USP2 | |
| SCHEMBL7924018 | 0.80 | ALDH1A1 (0.58) | MAPTNPSR1MEN1ALOX15KMT2A | |
| SCHEMBL7921879 | 0.79 | MEN1 (0.41) | POLBDRD2DRD3CYP3A4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221868-B1 | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-04-24 | — | — | US | disclosed |