SCHEMBL7925437

SCHEMBL7925437

C[Si]1(C)C2=Cc3ccccc3C2[Ti](OC(=O)c2cccc3ccccc23)(OC(=O)c2cccc3ccccc23)C2C1=Cc1ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
CDC25B P30305 3/20 0.36
NR4A1 P22736 1/20 0.36
NR4A2 P43354 1/20 0.36
NR4A3 Q92570 1/20 0.36
PLK1 P53350 1/20 0.36
ALDH1A1 P00352 4/20 0.35
HPGD P15428 4/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 3/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7927283 0.82 KMT2A (0.39) KMT2APOLBGAACDC25BNR4A1
SCHEMBL7931022 0.82 KMT2A (0.39) KMT2APOLBGAACDC25BNR4A1
SCHEMBL7925634 0.80 LMNA (0.37) KMT2APOLBGAAALDH1A1MAPT
SCHEMBL7930983 0.79 POLB (0.35) POLBALDH1A1LMNASMN1; SMN2
SCHEMBL7925894 0.76 RAB9A (0.36) KMT2APOLBGAAMAPTKDM4E
SCHEMBL7928240 0.76 ALDH1A1 (0.34) ALDH1A1LMNACYP3A4CYP2D6CYP2C9
SCHEMBL7930317 0.75 ELANE (0.31) MAPTLMNA
SCHEMBL7919525 0.75 ALDH1A1 (0.38) KMT2APOLBGAACDC25BNR4A1
SCHEMBL7928108 0.74 THRB (0.32) ALDH1A1LMNASMN1; SMN2
SCHEMBL7930273 0.72 KCNN4 (0.41) LMNACYP2D6CYP2C19KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed