Triaziquone

Triaziquone

SCHEMBL7925866

CC(=O)C(C)C(=O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.37
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
STAT3 P40763 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
APAF1 O14727 2/20 0.32
TDP2 O95551 2/20 0.32
NSD2 O96028 2/20 0.32
HKDC1 Q2TB90 2/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
GALK1 P51570 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
NOD2 Q9HC29 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL11583629 0.88 DNMT1 (0.41) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL6535620 0.86 DNMT1 (0.40) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL16419 0.86 MAPT (0.42) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL23091465 0.86 DNMT1 (0.36) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL112498 0.85 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL4082601 0.85 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL10414999 0.84 MAPT (0.41) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL424867 0.83 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL4608905 0.82 DNMT1 (0.43) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL5974054 0.82 DNMT1 (0.38) DNMT1TP53MAPTSTAT3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1064247-A1 TRANSESTERIFICATION PROCESS USING LANTHANUM COMPOUND CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-01-03 EP claimed
WO-1999047483-A1 TRANSESTERIFICATION PROCESS USING LANTHANUM COMPOUND CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-09-23 WO claimed
US-4040083-A ALUMINUM OXIDE LAYER BONDING POLYMER RESIN LAYER TO SEMICONDUCTOR DEVICE HITACHI, LTD. (JA) 1977-08-02 US claimed
CN-107431096-B Rectifier element, method for manufacturing the same, and wireless communication device 东丽株式会社 2021-01-15 CN disclosed
EP-1064247-A1 TRANSESTERIFICATION PROCESS USING LANTHANUM COMPOUND CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-01-03 EP disclosed
WO-1999047483-A1 TRANSESTERIFICATION PROCESS USING LANTHANUM COMPOUND CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-09-23 WO disclosed
US-4040083-A ALUMINUM OXIDE LAYER BONDING POLYMER RESIN LAYER TO SEMICONDUCTOR DEVICE HITACHI, LTD. (JA) 1977-08-02 US disclosed