Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | BUB1 | O43683 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14409096 | 1.00 | AGTR2 (0.46) | AGTR2GRM6GRM2BUB1CTSL | |
| SCHEMBL7936478 | 0.84 | AGTR2 (0.45) | AGTR2BUB1CTSLCTSBCTSK | |
| SCHEMBL7936553 | 0.82 | AGTR2 (0.43) | AGTR2BUB1CTSLCTSBCTSK | |
| SCHEMBL14409095 | 0.79 | AGTR2 (0.42) | AGTR2BUB1CTSLCTSBCTSK | |
| SCHEMBL9394261 | 0.79 | TSHR (0.48) | AGTR2BUB1CTSLCTSBCTSK | |
| SCHEMBL296907 | 0.78 | GRM2 (0.47) | GRM6GRM2CTSLCTSBCTSK | |
| SCHEMBL14409083 | 0.78 | GRM2 (0.47) | GRM6GRM2CTSLCTSBCTSK | |
| SCHEMBL599216 | 0.76 | TSHR (0.45) | AGTR2BUB1CTSLCTSBCTSK | |
| SCHEMBL15927872 | 0.76 | CTSL (0.51) | AGTR2CTSLCTSBCTSKTSHR | |
| SCHEMBL1613917 | 0.76 | TSHR (0.48) | AGTR2BUB1CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7264792-B2 | Solid phase preparation of 18F-labelled amino acids | GE HEALTHCARE LIMITED (GB) | 2007-09-04 | — | — | US | disclosed |
| EP-0862464-A4 | AMINO ACID ANALOGS FOR TUMOR IMAGING | UNIV EMORY (US) | 2001-07-25 | — | — | EP | disclosed |
| US-5817776-A | TECHNETIUM 99 COMPLEXES, SINGLE PHOTON EMISSION TOMOGRAPHY | EMORY UNIVERSITY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5808146-A | Amino acid analogs for tumor imaging | EMORY UNIVERSITY (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0862464-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997017092-A1 | AMINO ACID ANALOGS FOR TUMOR IMAGING | EMORY UNIVERSITY (US) | 1997-05-15 | — | — | WO | disclosed |