Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296907 | 1.00 | GRM2 (0.47) | GRM2GRM3GRM6DPP4EPHX2 | |
| SCHEMBL23274871 | 0.85 | EPHX2 (0.44) | GRM2GRM3DPP4EPHX2CTSL | |
| SCHEMBL7926366 | 0.84 | DPP4 (0.57) | GRM2GRM3GRM6DPP4EPHX2 | |
| SCHEMBL2640274 | 0.83 | EPHX2 (0.47) | GRM2GRM3DPP4EPHX2CTSL | |
| SCHEMBL15306513 | 0.83 | ADAM17 (0.45) | DPP4EPHX2ALDH1A1OPRM1OPRL1 | |
| SCHEMBL297404 | 0.83 | ADAM17 (0.45) | DPP4EPHX2ALDH1A1OPRM1OPRL1 | |
| SCHEMBL31471348 | 0.82 | EPHX2 (0.46) | GRM2GRM3DPP4EPHX2CTSL | |
| SCHEMBL2787488 | 0.81 | GRM2 (0.45) | GRM2GRM3DPP4EPHX2CTSL | |
| SCHEMBL19385743 | 0.81 | OPRM1 (0.46) | GRM2GRM3DPP4EPHX2CTSL | |
| SCHEMBL9960560 | 0.81 | EPHX2 (0.45) | GRM2GRM3DPP4EPHX2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11083804-B2 | Precursor compound of radioactive halogen-labeled organic compound | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2021-08-10 | — | — | US | disclosed |
| US-9238596-B2 | Process simplification for precursor compound | GE HEALTHCARE LIMITED (GB) | 2016-01-19 | — | — | US | disclosed |
| US-9061977-B2 | Purification of precursor compound by crystallisation | GE HEALTHCARE LIMITED (GB) | 2015-06-23 | — | — | US | disclosed |
| US-20130274507-A1 | PROCESS SIMPLIFICATION FOR PRECURSOR COMPOUND | GE HEALTHCARE LIMITED (GB) | 2013-10-17 | — | — | US | disclosed |
| US-20130267730-A1 | PURIFICIATION OF PRECURSOR COMPOUND BY CRYSTALLISATION | GE HEALTHCARE LIMITED (GB) | 2013-10-10 | — | — | US | disclosed |
| US-7264792-B2 | Solid phase preparation of 18F-labelled amino acids | GE HEALTHCARE LIMITED (GB) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11083804-B2 | Precursor compound of radioactive halogen-labeled organic compound | BCAT2, SLCO2B1, ORC3 | GRM2 1092/4885GRM3 2855/4885GRM6 2091/4885 |
| US-20130274507-A1 | PROCESS SIMPLIFICATION FOR PRECURSOR COMPOUND | PAICS, FGB, FIP1L1 | GRM2 3391/4885GRM3 2342/4885GRM6 2842/4885 |
| US-20130267730-A1 | PURIFICIATION OF PRECURSOR COMPOUND BY CRYSTALLISATION | RFC1, PAICS, RFC2 | GRM2 3358/4885GRM3 2947/4885GRM6 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.